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AP Biology Unit 3: Cellular Energetics — Tips & Strategies

7 tips
Concept

Cellular Respiration: Follow the Carbon

Glycolysis splits glucose into 2 pyruvate (cytoplasm). Pyruvate oxidation and the Krebs cycle release CO2 (mitochondrial matrix). The ETC produces most ATP (inner membrane).

Concept

Chemiosmosis: The Proton Gradient Powers ATP

Both photosynthesis and cellular respiration use an electron transport chain to pump H+ ions, creating a gradient. H+ flows back through ATP synthase, driving ATP production.

Common mistake

Fermentation Is NOT a Replacement for Aerobic Respiration

Fermentation only regenerates NAD+ so glycolysis can continue. It produces zero additional ATP. Total yield is just 2 ATP per glucose (from glycolysis alone).

Exam strategy

Photosynthesis Rate Factors: Light, CO2, Temperature

Photosynthesis rate is limited by whichever factor is least available (limiting factor principle). Graphs of rate vs. each variable plateau at saturation points.

Concept

Photosynthesis Overview: Two Stages, Two Locations

Light reactions occur in thylakoid membranes (produce ATP and NADPH). The Calvin cycle occurs in the stroma (uses ATP and NADPH to fix carbon into G3P).

Memorization

ETC Electron Carriers: Know the Order

In cellular respiration, electrons flow from NADH/FADH2 through complexes I-IV to oxygen (final electron acceptor). NADH enters at Complex I; FADH2 at Complex II.

Common mistake

Krebs Cycle Products Per Turn — Don't Over-Count

One turn of the Krebs cycle produces: 1 ATP (via GTP), 3 NADH, 1 FADH2, and 2 CO2. Since each glucose yields 2 acetyl-CoA, multiply everything by 2 for per-glucose totals.